Dr. Ettleson’s research interests include epidemiology and health services research in the diagnosis and treatment of thyroid disease. Specifically, his research is aimed at evaluating and improving the quality of care delivered to patients with hypothyroidism. He has investigated patterns in hypothyroidism treatment, medical decision making, and clinical outcomes. The ultimate goal of his research program is to optimize hypothyroidism treatment to improve the patient experience and reduce adverse outcomes. He is currently developing novel approaches to measure and improve the quality of levothyroxine treatment in hypothyroidism as part of a career development grant funded by the NIDDK. In the DCAM endocrinology clinic, Dr. Ettleson sees patients with general endocrinology conditions in the DCAM, with a focus on thyroid diseases, type 2 diabetes, and male hypogonadism.
A Longitudinal, Real-World Study of the Relationship between Levothyroxine Dose and Suboptimal Hypothyroidism Treatment.
A Longitudinal, Real-World Study of the Relationship between Levothyroxine Dose and Suboptimal Hypothyroidism Treatment. Thyroid. 2026 08; 36(8):832-839.
PMID: 42308153
Impact of Hypothyroidism on Short-Term and Long-Term Outcomes of Coronary Artery Bypass Graft Surgery.
Impact of Hypothyroidism on Short-Term and Long-Term Outcomes of Coronary Artery Bypass Graft Surgery. Thyroid. 2026 08; 36(8):862-871.
PMID: 42287021
A Phase 2 Study of XP-8121: Once-Weekly Subcutaneous Levothyroxine Sodium for the Treatment of Hypothyroidism in Adults.
A Phase 2 Study of XP-8121: Once-Weekly Subcutaneous Levothyroxine Sodium for the Treatment of Hypothyroidism in Adults. Thyroid. 2026 08; 36(8):853-861.
PMID: 42236452
Suboptimal Levothyroxine Treatment is Associated with Increases in Mean Blood Pressure and Blood Pressure Variability.
Suboptimal Levothyroxine Treatment is Associated with Increases in Mean Blood Pressure and Blood Pressure Variability. J Clin Endocrinol Metab. 2026 May 19; 111(6):e1626-e1633.
PMID: 41403148
Distribution of Outpatient Visits Among Adults With Hypothyroidism: NAMCS 2010-2019.
Distribution of Outpatient Visits Among Adults With Hypothyroidism: NAMCS 2010-2019. AACE Endocrinol Diabetes. 2026 Jul-Aug; 13(4):575-578.
PMID: 42491786
The Incidence of Cardiovascular Disease Events in Women with Hypothyroidism: The Study of Women's Health Across the Nation.
The Incidence of Cardiovascular Disease Events in Women with Hypothyroidism: The Study of Women's Health Across the Nation. Thyroid. 2026 03; 36(3):251-258.
PMID: 41735798
Adverse Outcomes in Patients With Hypothyroidism Undergoing Bariatric Surgery: A Retrospective Study Using TriNetX.
Adverse Outcomes in Patients With Hypothyroidism Undergoing Bariatric Surgery: A Retrospective Study Using TriNetX. J Clin Endocrinol Metab. 2026 Feb 20; 111(3):e766-e777.
PMID: 40971953
Measuring Hypothyroidism Disease Control Using a TSH-based "Time-in-range".
Measuring Hypothyroidism Disease Control Using a TSH-based "Time-in-range". J Clin Endocrinol Metab. 2026 Jan 21; 111(2):e484-e492.
PMID: 40645612
Treatment of Hypothyroidism That Contains Liothyronine is Associated With Reduced Risk of Dementia and Mortality.
Treatment of Hypothyroidism That Contains Liothyronine is Associated With Reduced Risk of Dementia and Mortality. J Clin Endocrinol Metab. 2026 Jan 21; 111(2):561-571.
PMID: 40579157
Lower Serum Triiodothyronine Levels Constitute an Independent Risk Factor for Dyslipidemia in Levothyroxin-Treated Patients.
Lower Serum Triiodothyronine Levels Constitute an Independent Risk Factor for Dyslipidemia in Levothyroxin-Treated Patients. Endocr Pract. 2026 Feb; 32(2):135-141.
PMID: 40774617