Gaurav A Upadhyay, MD

GAURAV A. UPADHYAY, MD, FACC, FHRS is an expert in cardiac rhythm devices and Associate Professor at the University of Chicago Medicine. He is Vice Chief of Cardiology, Promotions & Appointments. He is the Director of the Pacing & Defibrillation Device Clinic and also Director of the Heart Station, overseeing ambulatory monitoring and ECGs Dr. Upadhyay’s clinical research interests include elucidating mechanisms and approaches for conduction system pacing (CSP), device optimization strategies for cardiac resynchronization therapy (CRT) in heart failure, autonomic modulation for syncope and arrhythmia, and large database analysis for catheter ablation of arrhythmias including atrial fibrillation.

Paralleling his focus on patient care, Dr. Upadhyay is an active clinical investigator. An invited national and international speaker, he has authored or delivered over 300 manuscripts, editorials, book chapters, and abstracts. He is also deeply committed to teaching, and seeks out opportunities to collaborate and engage trainees in teaching at the bedside as well as in transforming models of care.

EDUCATION

Medical Degree: University of Chicago Pritzker School of Medicine

Program in Clinical Effectiveness: Harvard T. H. Chan School of Public Health

Residency: Massachusetts General Hospital, Harvard Medical School

Cardiology Fellowship: Massachusetts General Hospital, Harvard Medical School

Electrophysiology Fellowship: Massachusetts General Hospital, Harvard Medical School

Left Septal Recordings in HBP Versus LBBAP: Highlighting the Need for a Modified Nomenclature.
Left Septal Recordings in HBP Versus LBBAP: Highlighting the Need for a Modified Nomenclature. JACC Clin Electrophysiol. 2025 Apr 03.
PMID: 40272317

Importance of Prolonged QRS Duration in Detecting Complete Conduction Block-Reply.
Importance of Prolonged QRS Duration in Detecting Complete Conduction Block-Reply. JAMA Cardiol. 2024 Dec 01; 9(12):1172.
PMID: 39292492

Comparing outcomes after pulmonary vein isolation in patients with systolic and diastolic heart failure.
Comparing outcomes after pulmonary vein isolation in patients with systolic and diastolic heart failure. Heart Rhythm O2. 2024 Aug; 5(8):529-537.
PMID: 39263616

A Revised Definition of Left Bundle Branch Block Using Time to Notch in Lead I.
A Revised Definition of Left Bundle Branch Block Using Time to Notch in Lead I. JAMA Cardiol. 2024 May 01; 9(5):449-456.
PMID: 38536171

What Intracardiac Tracings Have Taught Us About Left Bundle Branch Block.
What Intracardiac Tracings Have Taught Us About Left Bundle Branch Block. Card Electrophysiol Clin. 2022 06; 14(2):203-211.
PMID: 35715078

Impact of physiological pacing on functional mitral regurgitation in systolic dysfunction: Initial echocardiographic remodeling findings after His bundle pacing.
Impact of physiological pacing on functional mitral regurgitation in systolic dysfunction: Initial echocardiographic remodeling findings after His bundle pacing. Heart Rhythm O2. 2021 Oct; 2(5):446-454.
PMID: 34667959

Bradyarrhythmias and Physiologic Pacing in the ICU.
Bradyarrhythmias and Physiologic Pacing in the ICU. J Intensive Care Med. 2022 May; 37(5):595-610.
PMID: 33813926