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| There is a diversity of research activities within the Section of Infectious Diseases and Global Health. Investigations range from basic laboratory studies, outbreak investigations-often utilizing state-of-the-art molecular methods for strain typing, clinical trials, and hospital epidemiology. Basic lab investigations into the mechanisms of probiotic formulations in inflammatory bowel disease are being conducted in a collaborative effort with the Section of Gastroenterology. Clinical studies include determining factors that affect adherence with antiretroviral regimens, studies of new antiretroviral therapies for HIV infection, and studies of the safety and efficacy of new antimicrobial agents. The section is collaborating with Transplant Surgery in a multi-center study of solid organ transplantation of HIV-infected patients. There is also translational research in immunodeficiency states, with laboratory studies of ex vivo leukocyte apoptosis and immune reconstitution in HIV infection and phagocytic cell function in transplant recipients. Active epidemiologic investigations include the epidemiology of VRE in the Bone Marrow Transplant unit, epidemiology of other antibiotic-resistant pathogens, and risk factor analysis for hospital-acquired fungal infections. | ||
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