Basic Research

The basic research in the Section of Rheumatology focuses on the biology of T and B lymphocytes. Lymphocytes are essential for the elimination of microbial pathogens and tumors, but are also responsible for the development of autoimmune diseases and the rejection of transplanted organs. Understanding how T and B lymphocytes develop and become activated is important to create the new generation of immunosuppressive agents that target selective lymphocytes responsible for disease.

The basic research team comprises Marcus Clark, M.D., Chief of the Section of Rheumatology and Professor of Medicine, Maria-Luisa Alegre, M.D., Ph.D., Professor of Medicine, Fotini Gounari, Ph.D., Associate Professor of Medicine, and Patrick Wilson, Ph.D., Associate Professor.