$10 Million Gift Accelerates Research to Improve Cancer Therapies

The  UChicago Medicine has received a $10 million gift to establish the David and Etta Jonas Center for Cellular Therapy to support research to find personalized therapies for difficult-to-treat cancers. Michael Bishop, MD,  Professor of Medicine (Section of Hematology/Oncology) will serve as director of the new Jonas Center. He will be working with Amittha Wickrema, PhD, Professor of Medicine (Section of Hematology/Oncology), as well as Hans Schreiber, MD, PhD, in the Department of Pathology, and other colleagues to expand cell therapy to solid tumors and expand the number of patients who can benefit from the treatment. The center — named … Read More

UChicago Medicine doctors see ‘truly remarkable’ success using ventilator alternatives to treat COVID-19

Doctors at the University of Chicago Medicine are seeing “truly remarkable” results using high-flow nasal cannulas rather than ventilators and intubation to treat some COVID-19 patients. High-flow nasal cannulas, or HFNCs, are non-invasive nasal prongs that sit below the nostrils and blow large volumes of warm, humidified oxygen into the nose and lungs. A team from UChicago Medicine’s emergency room took dozens of COVID-19 patients who were in respiratory distress and gave them HFNCs instead of putting them on ventilators. The patients all fared extremely well, and only one of them required intubation after 10 days. “The success we’ve had … Read More

Karen E. Kim,MD Appointed Vice Provost for Research

Karen Kim, MD, Professor of Medicine in the Section of Gastroenterology, Hepatology and Nutrition and Dean for Faculty Affairs for the Division of the Biological Sciences, has been appointed as  Vice Provost for Research, effective March 9,2020 . In this role, Dr. Kim will work with faculty and deans to support and enhance external research funding and manage large-scale research structures such as University Research Administration (URA) and the University of Chicago Consortium for Advanced Science and Engineering (CASE), the Office of Research Safety, Research Computing Center, and Research Development Support. Dr. Kim  has served as Associate Director of the … Read More

Antonio Bianco,MD,PhD to Receive the American Thyroid Association‘s 2020 John B. Stanbury Thyroid Pathophysiology Medal

Antonio Bianco,MD,PhD has been selected as the recipient of the  American Thyroid Association‘s 2020 John B. Stanbury Thyroid Pathophysiology Medal in recognition of his extraordinary contributions to thyroid disease research. Dr. Bianco, professor of medicine in the Section of Endocrinology, Diabetes and Metabolism, is an internationally recognized expert in the study of thyroid hormone action, particularly in the local control of thyroid hormone activation by deiodinase enzymes.  He is a Past President of the American Thyroid Association and a former recipient of the Van Meter Award from the American Thyroid Association, the Rosalind-Pitts-Rivers Medal from the British Thyroid Association, and … Read More

Shifts in chemical rhythms may cause eating behaviors that lead to obesity

Obesity is a common health problem affecting over 90 million adults in the United States, However, how different chemical signals in the body respond to this disease continues to remain unclear. A new study from researchers at the University of Chicago published in the Journal of Clinical Endocrinology and Metabolism helps to untangle how part of the nervous system changes in adults affected by obesity, and what role this plays in appetite, eating behaviors, and even sleep cycles. The endocannabinoid system is a part of the nervous system that helps to regulate many processes in the body including appetite, pain and the immune … Read More

COVID-19 Resource Center

Below is a current list of resources available relating to COVID-19. Outpatient COVID Training 4 6 http://guides.lib.uchicago.edu/covid19/clinicians https://uchicago.app.box.com/s/qaq9vwged2jctkulmlfyms3gc9wlkktx https://uchicago.app.box.com/s/cn9oihv45p6p3x9wpz15610lx92ciy6x RESOURCE HOW TO ACCESS USE Coronavirus Resource Center home.uchospitals.edu and click box in the top/center or visit this link. Central repository for all UCM clinical material about COVID-19, including SOPs, videos, etc. General Coronavirus Email coronavirus@uchospitals.edu General staff questions about UCM/BSD response to the outbreak 24/7 Staff Resource Line 1-800-683-5704 Questions that cannot be answered on the unit level COVID-19 Teletriage 773-702-2800 (Patients) 773-702-6819 (Employees who need to schedule testing appointments) Screening employees and current patients for COVID-19 symptoms and scheduling … Read More

2020 Janet D. Rowley Research Day Abstract Winners

Congratulations to the Janet D. Rowley Research Day Best Abstract Winners: Faculty: Joseph Wynne,MD,PhD (Hematology/ Oncology)- Basic Research: “Targeting BACH1 inhibits HIF-induced tumor hypoxia and improves radiation treatment in triple negative breast cancer (TNBC)” Felicia D’Souza,MD (Hospital Medicine)-Clinical Research: “Appropriateness and Safety of Direct Access Endoscopy (DAE) in Hospitalized Patients” Kimberly Stanford, MD (Emergency Medicine)-Health Services Research:   Routine HIV testing in Emergency Department relies on effective electronic medical record prompts, provider buy-in, and dedicated staff follow-up” Alexander Pearson,MD,PhD (Hematology/Oncology)-Translational Research: “Deep learning detects actionable molecular and clinical states directly from head/neck squamous cell carcinoma histopathology slides”   Trainees: Xiaoou Li,MD,PhD … Read More

Breakthrough mouse model of celiac disease could lead to new treatments

Researchers in the Department of Medicine  have developed the first truly accurate mouse model of celiac disease. The animals have the same genetic and immune system characteristics as humans who develop celiac after eating gluten. This provides a vital research tool for developing and testing new treatments for the disease. “Based on our understanding of the human disease, we were able to retro-engineer a mouse model of celiac disease,” said Bana Jabri, MD, PhD, Director of Research at the University of Chicago Medicine Celiac Disease Center and senior author of the new study, published this week in Nature. “It’s the first model where the … Read More

Department of Medicine ranks #17 in 2019 NIH Funding

The Department of Medicine was ranked  #17 in 2019 NIH funding among departments of internal medicine in the latest data released by Blue Ridge Institute for Medical Research. This ranking, representing $92.4 million in NIH awards, is the Department’s highest ranking since 2012 when we ranked #15.  Within the Chicago area, Northwestern ranks #20, UIC #51 and Rush #70. In the Midwest, Washington University ranks #11, the University of Michigan #18, the University of Wisconsin #21, Indiana University-Purdue University at Indianapolis #29 and the University of Iowa as #41.  UCSF ranked #1 with over $216.4M followed by Vanderbilt with $175.1M in … Read More

Three Department of Medicine Faculty Elected to AAP

Three Department of Medicine faculty were recently elected to the Association of American Physicians (AAP): Marisa Alegre, MD, PhD, Gokhan Mutlu, MD and Thomas Gajewski,MD,PhD. The AAP is an honorific, elected society of America’s leading physician-scientists who exemplify the pinnacle of pioneering and enduring, impactful contributions to improve health. Dr. Alegre, Professor of Medicine in the Section of Rheumatology, is a leader in the field of transplantation immunology. Stemming from her clinical training as an intensivist and her basic immunology training, she addresses critical clinical questions with new mouse models of solid organ transplantation. This has led to several paradigm-shifting … Read More