Formula for predicting survival in patient with pulmonary arterial hypertension

The landmark registry developed in 1980, the National institutes of Health (NIH) Registry, lead by Dr. Stuart Rich, now practicing at the University of Chicago, evaluated patients with primary pulmonary hypertension (PPH), which represents idiopathic, familial and anorexigen related PAH under the recent World Health Organization classification. Several contemporary registries of patients with PAH have observed improved survival in the current era compared to the NIH registry (including ours at the University of Chicago) http://www.ncbi.nlm.nih.gov/pubmed/17804449 PMID: 17804449 [PubMed - indexed for MEDLINE] questioning the validity of the NIH equation as an accurate predictor of survival in patients with idiopathic, familial, and anorexigen-associated PAH. Since the NIH equation appears to underestimates survival, we developed a new regression equation, the PHC calculator, to predict survival in patients with idiopathic, familial, and anorexigen-associated PAH in the current era using our Chicago registry. Hemodynamics best predicted survival even after evaluating measures of exercise capacity and other previously identified predictors.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=20032020

Below is the calculator for your use.



mPAP (mm Hg):
mRAP (mm Hg):
CI (L/Min/m2):
 

Survival Probablity Over Time

1 Year 2 Year 3 Year 4 Year 5 Year